N-Succinimidyl 4-Azido-2,3,5,6-tetrafluorobenzoate

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Catalogue number: PA 27 0031203
Chemical name: N-Succinimidyl 4-Azido-2,3,5,6-tetrafluorobenzoate

CAS Number:

126695-58-7

Category: miscellaneous compounds,Antibody Drug Conjugate
Synonyms:

Benzoic acid, 4-azido-2,3,5,6-tetrafluoro-, 2,5-dioxo-1-pyrrolidinyl ester; 2,5-Pyrrolidinedione, 1-[(4-azido-2,3,5,6-tetrafluorobenzoyl)oxy]-; 4-Azido-tetrafluorobenzoate N-hydroxysuccinimidyl ester; N-Succinimidyl 4-azidotetrafluorobenzoate; ATFB-SE;

Molecular form: C11H4F4N4O4
Appearance: NA
Mol. Weight: 332.17
Storage: 2-8°C Refrigerator
Shipping Conditions: Ambient
Applications: 4-N3Pfp-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. 4-N3Pfp-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups

N-Succinimidyl 4-Azido-2,3,5,6-tetrafluorobenzoate

126695-58-7
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