| Catalogue number: | PA STI 086780 |
| Chemical name: | Vemurafenib-d5 |
CAS Number: |
1365986-90-8 |
| Category: | aromatics,heterocycles,protein kinase inhibitors and activators,sulphur and selenium compounds,pharmaceutical standards,intermediates,fine chemicals,stable isotopes |
| Synonyms: | N-[3-[[5-(4-Chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide-d5; PLX 4032-d5; RG 7204-d5; Ro 51-85426-d5; |
| Molecular form: | C23H13D5ClF2N3O3S |
| Appearance: | NA |
| Mol. Weight: | 494.95 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | Labelled Vemurafeni, a selective BRAFV600E kinase inhibitor; an antitumor agent. Vemurafenib functions by inhibiting the proliferation and mitogen-activated protein/extracellular signal-regulated kinase (ERK) kinase and ERK phosphorylation in a panel of tumor cell lines, including melanoma cell lines expressing BRAFV600E or other mutant BRAF proteins altered at codon 600. |
| BTM: | NA |
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