| Catalogue number: | PA PEP 002519 |
| Chemical name: | Zoptarelin doxorubicin |
CAS Number: |
139570-93-7 |
| Category: | peptides,Antibody Drug Conjugate |
| Synonyms: | 2-((2S,4S)-4-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-2-yl)-2-oxoethyl (3S,6S,9S,12S,15R)-3-((1H-imidazol-5-yl)methyl)-6-((1H-indol-3-yl)methyl)-15-(((S)-1-(((S)-1-((S)-2-((2-amino-2-oxoethyl)carbamoyl)pyrrolidin-1-yl)-5-guanidino-1-oxopentan-2-yl)amino)-4-methyl-1-oxopentan-2-yl)carbamoyl)-12-(4-hydroxybenzyl)-9-(hydroxymethyl)-1,4,7,10,13,21-hexaoxo-1-((S)-5-oxopyrrolidin-2-yl)-2,5,8,11,14,20-hexaazapentacosan-25-oate; Luteinizing hormone-releasing factor (swine), 6-[N6-[5-[2-[(2S,4S)-4-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenyl]-2-oxoethoxy]-1,5-dioxopentyl]-D-lysine]-; Luteinizing hormone-releasing factor (human), 6-[N6-[5-[2-[(2S,4S)-4-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenyl]-2-oxoethoxy]-1,5-dioxopentyl]-D-lysine]-; Zoptrex; |
| Molecular form: | C91H117N19O26 |
| Appearance: | NA |
| Mol. Weight: | 1893.04 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | Zoptarelin doxorubicin (AEZS-108; AN-152) is a hybrid anticancer agent, containing Zoptarelin and Doxorubicin. Zoptarelin doxorubicin has been used to research targeting tumors expressing LHRH receptors. Zoptarelin doxorubicin abolishes tumor progression and induces remarkable apoptosis in vitro |
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