MMAF hydrochloride

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Catalogue number:	PA PEP 002527
Chemical name:	MMAF hydrochloride
CAS Number:	1415246-68-2
Category:	peptides,Antibody Drug Conjugate
Synonyms:	L-Phenylalanine, N-methyl-L-valyl-L-valyl-(3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino)heptanoyl-(αR,βR,2S)-β-methoxy-α-methyl-2-pyrrolidinepropanoyl-, hydrochloride (1:1); ((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-N,3-dimethyl-2-((S)-3-methyl-2-(methylamino)butanamido)butanamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanoyl)-L-phenylalanine hydrochloride;
Molecular form:	C₃₉H₆₆ClN₅O₈
Appearance:	Solid
Mol. Weight:	768.43
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	MMAF (Monomethylauristatin F) hydrochloride is a potent tubulin polymerization inhibitor and is used as a antitumor agent. MMAF hydrochloride is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) such as Vorsetuzumab mafodotin and SGN-CD19A