Catalogue number: | PA 27 0018389 |
Chemical name: | trans-4-[2-(Butylamino)-5-[4-[(4-methyl-1-piperazinyl)methyl]phenyl]-7H-pyrrolo[2,3-d]pyrimidin-7-yl]cyclohexanol |
CAS Number: |
1429881-91-3 |
Category: | enzyme activators,enzyme inhibitors,pharmaceutical standards,impurities,metabolites,fine chemicals |
Synonyms: | (1r,4r)-4-(2-(Butylamino)-5-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)cyclohexan-1-ol; |
Molecular form: | C28H40N6O |
Appearance: | NA |
Mol. Weight: | 476.67 |
Storage: | 2-8°C Refrigerator |
Shipping Conditions: | Ambient |
Applications: | UNC 2025 is Mer/FLT3 dual inhibitor. It can be used in biological study. Novel MERTK inhibitor UNC2025 induced polyploidy and promoted death and senescence in human glioblastoma multiforme cells where high levels of GAS6 MERTK ligand expression correlated with decreased overall survival in patients. |
BTM: | NA |
trans-4-[2-(Butylamino)-5-[4-[(4-methyl-1-piperazinyl)methyl]phenyl]-7H-pyrrolo[2,3-d]pyrimidin-7-yl]cyclohexanol
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