| Catalogue number: | PA 27 0031500 |
| Chemical name: | NMS-P945 |
CAS Number: |
1466546-35-9 |
| Category: | miscellaneous compounds,Antibody Drug Conjugate |
| Synonyms: | L-Ornithinamide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[[[2-[[[[(8S)-8-(chloromethyl)-7,8-dihydro-1-methyl-6-[[5-[2-(1-pyrrolidinyl)ethoxy]-1H-indol-2-yl]carbonyl]-6H-thieno[3,2-e]indol-4-yl]oxy]carbonyl]methylamino]ethyl]methylamino]carbonyl]oxy]methyl]phenyl]-; N-[6-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[[[2-[[[[(8S)-8-(chloromethyl)-7,8-dihydro-1-methyl-6-[[5-[2-(1-pyrrolidinyl)ethoxy]-1H-indol-2-yl]carbonyl]-6H-thieno[3,2-e]indol-4-yl]oxy]carbonyl]methylamino]ethyl]methylamino]carbonyl]oxy]methyl]phenyl]-L-ornithinamide; (S)-8-(chloromethyl)-1-methyl-6-(5-(2-(pyrrolidin-1-yl)ethoxy)-1H-indole-2-carbonyl)-7,8-dihydro-6H-thieno[3,2-e]indol-4-yl (4-((S)-2-((S)-2-(6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamido)-3-methylbutanamido)-5-ureidopentanamido)benzyl) ethane-1,2-diylbis(methylcarbamate); |
| Molecular form: | C61H76ClN11O12S |
| Appearance: | NA |
| Mol. Weight: | 1222.85 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | NMS-P945 is an ADC linker that can be used in the synthesis of antibody-drug conjugates (ADCs). NMS-P945 is suitable for conjugation to mAbs with reproducible Drug Antibody Ratio (DAR) >3.5[1] |
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