Name: NMS-P945
Brand: Pharmaffliates
Rating: 4.00 (5 reviews)

Catalogue number:	PA 27 0031500
Chemical name:	NMS-P945
CAS Number:	1466546-35-9
Category:	miscellaneous compounds,Antibody Drug Conjugate
Synonyms:	L-Ornithinamide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[[[2-[[[[(8S)-8-(chloromethyl)-7,8-dihydro-1-methyl-6-[[5-[2-(1-pyrrolidinyl)ethoxy]-1H-indol-2-yl]carbonyl]-6H-thieno[3,2-e]indol-4-yl]oxy]carbonyl]methylamino]ethyl]methylamino]carbonyl]oxy]methyl]phenyl]-; N-[6-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[[[2-[[[[(8S)-8-(chloromethyl)-7,8-dihydro-1-methyl-6-[[5-[2-(1-pyrrolidinyl)ethoxy]-1H-indol-2-yl]carbonyl]-6H-thieno[3,2-e]indol-4-yl]oxy]carbonyl]methylamino]ethyl]methylamino]carbonyl]oxy]methyl]phenyl]-L-ornithinamide; (S)-8-(chloromethyl)-1-methyl-6-(5-(2-(pyrrolidin-1-yl)ethoxy)-1H-indole-2-carbonyl)-7,8-dihydro-6H-thieno[3,2-e]indol-4-yl (4-((S)-2-((S)-2-(6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamido)-3-methylbutanamido)-5-ureidopentanamido)benzyl) ethane-1,2-diylbis(methylcarbamate);
Molecular form:	C₆₁H₇₆ClN₁₁O₁₂S
Appearance:	NA
Mol. Weight:	1222.85
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	NMS-P945 is an ADC linker that can be used in the synthesis of antibody-drug conjugates (ADCs). NMS-P945 is suitable for conjugation to mAbs with reproducible Drug Antibody Ratio (DAR) >3.5[1]

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