In House Impurity
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Catalogue number: PA 06 0961007
Chemical name: 1-(2-Iodoethyl)-2-octylbenzene

CAS Number:


Alternate CAS Number: NA
Category: intermediates,impurities,metabolites,pharmaceutical standards,fine chemicals

2-Octylphenethyl iodide;

Molecular form: C16H25I
Appearance: NA
Mol. Weight: 344.28
Storage: 2-8°C Refrigerator
Shipping Conditions: Ambient
Applications: 1-​(2-​Iodoethyl)​-​2-​octylbenzene is an impurity of Fingloimod (F805000), also known as FTY720. FTY720 is a derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analogue of Sphingosine. FTY720 is a novel immune modulator that prolongs allograft transplant survival in numberour models by inhibiting lymphocyte emigration from lymphoid organs. FTY720 us reported to be phosphorylated by sphingosine kinase to FTY720-P, which has been shown to potently stimulate GTPgS binding activity in S1P-transfected CHO cells (EC50 = 210 pM, 4.9 nM, 4.3 nM, and 1 nM for S1P1, S1P3, S1P4 and S1P5, respectively).


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