| Catalogue number: | PA 27 0032082 |
| Chemical name: | NH2-NODA-GA |
CAS Number: |
1630114-57-6 |
| Category: | miscellaneous compounds,Antibody Drug Conjugate |
| Synonyms: | 2,2'-(7-(4-((2-Aminoethyl)amino)-1-carboxy-4-oxobutyl)-1,4,7-triazonane-1,4-diyl)diacetic acid; 1H-1,4,7-Triazonine-1,4,7-triacetic acid, α1-[3-[(2-aminoethyl)amino]-3-oxopropyl]hexahydro-; α1-[3-[(2-Aminoethyl)amino]-3-oxopropyl]hexahydro-1H-1,4,7-triazonine-1,4,7-triacetic acid; |
| Molecular form: | C17H31N5O7 |
| Appearance: | NA |
| Mol. Weight: | 417.46 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | NH2-NODAGA is a NODAGA-type metal chelator that can bind to radionuclides to prepare radionuclide conjugates (RDCs). NH2-NODAGA can react with diethyl squarate in 0.5M phosphate buffer (room temperature, 2 h, pH 7-7.5) to obtain NODAGA.SA. NODAGA.SA can target L-lysine urea-L-glutamate (KuE), which is a key structure of prostate-specific membrane antigen (PSMA). NODAGA.SA.KuE can bind [68]Ga and can be used for PET examination of NMRInu/nu nude mice bearing LNCaP tumors. |
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NH2-NODA-GA
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