Catalogue number: | PA PHY 004883 |
Chemical name: | Combretastatin A4 Phosphate Disodium Salt |
CAS Number: |
168555-66-6 |
Alternate CAS Number: | 222030-63-9 (Free Acid) |
Category: | NA |
Synonyms: | Disodium,[2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl] phosphate; |
Molecular form: | C18H19Na2O8P |
Appearance: | White to Off-White Solid |
Mol. Weight: | 440.3 |
Storage: | 2-8°C Refrigerator |
Shipping Conditions: | Ambient |
Applications: | Phosphorylated Combretastatin, a small organic molecule found in the bark of the African bush willow tree Combretum caffrum. Combretastatin-A4 Prodrug Induces Mitotic Catastrophe in Chronic Lymphocytic Leukemia Cell Line Independent of Caspase Activation and Poly(ADP-ribose) Polymerase Cleavage. A potent cytotoxic agent which strongly inhibits the polymerization of tubulin by binding to the colchicine site. |
Combretastatin A4 Phosphate Disodium Salt
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