Tetrazine-biotin

In House Impurity

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Catalogue number:	PA 02 0751087
Chemical name:	Tetrazine-biotin
CAS Number:	1714123-51-9
Category:	intermediates,pharmaceutical standards,Fine Chemicals,biotin derivatives,Antibody Drug Conjugate
Synonyms:	N-(4-(1,2,4,5-Tetrazin-3-yl)benzyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide; 1H-Thieno[3,4-d]imidazole-4-pentanamide, hexahydro-2-oxo-N-[[4-(1,2,4,5-tetrazin-3-yl)phenyl]methyl]-, (3aS,4S,6aR)-; (3aS,4S,6aR)-Hexahydro-2-oxo-N-[[4-(1,2,4,5-tetrazin-3-yl)phenyl]methyl]-1H-thieno[3,4-d]imidazole-4-pentanamide;
Molecular form:	C₁₉H₂₃N₇O₂S
Appearance:	Solid
Mol. Weight:	413.5
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	Tetrazine-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Tetrazine-biotin is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.