| Catalogue number: | PA 13 2910000 |
| Chemical name: | Metergoline |
CAS Number: |
17692-51-2 |
| Category: | amines,aromatics,impurities,pharmaceutical standards,intermediates |
| Synonyms: | Metergolin; Methergoline; D-N-Carboxydihydro-1-methyllysergamine I benzyl ester; D-[(4,6,6a,7,8,9,10,10a-Octahydro-4,7-dimethyl-10aα-indolo[4,3-fg]quinolin-9β-yl)methyl]carbamic acid benzyl ester; benzyl (((6aR,9S,10aR)-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)methyl)carbamate; Lysergamine, N-carboxy-9,10-dihydro-1-methyl-, benzyl ester; D-8β-[(Carbobenzoxyamino)methyl]-1,6-dimethyl-10α-ergoline; |
| Molecular form: | C25H29N3O2 |
| Appearance: | White to Off-White Solid |
| Mol. Weight: | 403.53 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | Metergoline is an ergot-derived psychoactive drug that acts as a ligand for serotonin and dopamine receptors. Metergoline is an antagonist at various 5-HT receptor subtypes at a relatively low concentration and agonist at dopamine receptors.3 Its use has been studied in various clinical settings such as a treatment for seasonal affective disorder, prolactin hormone regulation due to its inhibitory effect on prolactin release,1 premenstrual dysphoric disorder in women and antianxiety treatment. |
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