| Catalogue number: | PA 27 0032208 |
| Chemical name: | TAM470 |
CAS Number: |
1802498-63-0 |
| Category: | miscellaneous compounds,Antibody Drug Conjugate |
| Synonyms: | N-((2R,4S)-5-Hydrazineyl-1-(4-hydroxyphenyl)-4-methyl-5-oxopentan-2-yl)-2-((1R,3R)-4-methyl-3-((2S,3S)-3-methyl-2-((R)-1-methylpiperidine-2-carboxamido)-N-propylpentanamido)-1-propoxypentyl)thiazole-4-carboxamide; Benzenepentanoic acid, 4-hydroxy-α-methyl-γ-[[[2-[(1R,3R)-4-methyl-3-[[(2S,3S)-3-methyl-2-[[[(2R)-1-methyl-2-piperidinyl]carbonyl]amino]-1-oxopentyl]propylamino]-1-propoxypentyl]-4-thiazolyl]carbonyl]amino]-, hydrazide, (αS,γR)-; (αS,γR)-4-Hydroxy-α-methyl-γ-[[[2-[(1R,3R)-4-methyl-3-[[(2S,3S)-3-methyl-2-[[[(2R)-1-methyl-2-piperidinyl]carbonyl]amino]-1-oxopentyl]propylamino]-1-propoxypentyl]-4-thiazolyl]carbonyl]amino]benzenepentanoic acid hydrazide; |
| Molecular form: | C41H67N7O6S |
| Appearance: | Solid |
| Mol. Weight: | 786.09 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | TAM470 is a novel cytolysin, inhibiting tubulin polymerization and microtubule depolymerization. TAM470 can be used in the synthesis of OMTX705 as payload molecule, OMTX705 is a novel FAP-targeting antibody-drug conjugates (ADCs) with antitumor activity |
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