Name: Elvucitabine - API Standards
Brand: Pharmaffliates
Rating: 4.00 (5 reviews)

Catalogue number:	PA 05 1960000
Chemical name:	Elvucitabine
CAS Number:	181785-84-2
Category:	impurities,metabolites,pharmaceutical standards,intermediates,Fine Chemicals
Synonyms:	4-Amino-5-fluoro-1-((2S,5R)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl)pyrimidin-2(1H)-one; 2(1H)-Pyrimidinone, 4-amino-1-[2,5-dihydro-5-(hydroxymethyl)-2-furanyl]-5-fluoro-,(2S-cis);
Molecular form:	C₉H₁₀FN₃O₃
Appearance:	NA
Mol. Weight:	227.2
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	lvucitabine is a L-cytosine Nucleoside analog Reverse Transcriptase Inhibitor (NRTIs) anti-HIV drug. NRTI's inhibit the activity of viral RNA-directed DNA polymerase (i.e., reverse transcriptase). It is believed that inhibition of reverse transcriptase interferes with the generation of DNA copies of viral RNA, which, in turn, are necessary for synthesis of new virions. Intracellular enzymes subsequently eliminate the HIV particle that previously had been uncoated, and left unprotected, during entry into the host cell. Thus, reverse transcriptase inhibitors are virustatic and do not eliminate HIV from the body.

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