N-(3-Fluoro-7-(hydroxyimino)-4-methyl-8-oxo-5,6,7,8-tetrahydronaphthalen-1-yl)acetamide

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Catalogue number: PA 27 0032237
Chemical name: N-(3-Fluoro-7-(hydroxyimino)-4-methyl-8-oxo-5,6,7,8-tetrahydronaphthalen-1-yl)acetamide

CAS Number:

182182-32-7

Category: miscellaneous compounds,Antibody Drug Conjugate
Synonyms:

N-(3-Fluoro-7-(hydroxyimino)-4-methyl-8-oxo-5,6,7,8-tetrahydronaphthalen-1-yl)acetamide; Acetamide, N-[3-fluoro-5,6,7,8-tetrahydro-7-(hydroxyimino)-4-methyl-8-oxo-1-naphthalenyl]-; N-[3-Fluoro-5,6,7,8-tetrahydro-7-(hydroxyimino)-4-methyl-8-oxo-1-naphthalenyl]acetamide;

Molecular form: C13H13FN2O3
Appearance: Solid
Mol. Weight: 264.26
Storage: 2-8°C Refrigerator
Shipping Conditions: Ambient
Applications: Exatecan Intermediate 7 is the intermediate of Exatecan (HY-13631) And Exatecan (DX-8951) is a DNA topoisomerase I inhibitor with an IC50 value of 2.2 μM (0.975 μg/mL) that can be used in cancer research. Exatecan Intermediate 7 can be used to synthesize Antibody-Drug Conjugates (ADCs)

N-(3-Fluoro-7-(hydroxyimino)-4-methyl-8-oxo-5,6,7,8-tetrahydronaphthalen-1-yl)acetamide

182182-32-7
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