| Catalogue number: | PA 13 2170000 |
| Chemical name: | Mithramycin A |
CAS Number: |
18378-89-7 |
| Category: | impurities,metabolites,pharmaceutical standards,intermediates,Fine Chemicals |
| Synonyms: | Plicamycin; Plicatomycin; Aureolic Acid; Mithracin; Mitramycin; (2S,3S)-3-((1S,3S,4R)-3,4-Dihydroxy-1-methoxy-2-oxopentyl)-2-(((2S,4R,5R,6R)-4-(((2S,4R,5S,6R)-4-(((2S,4S,5R,6R)-4,5-dihydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6-(((2S,4R,5R,6R)-4-(((2S,4R,5S,6R)-4,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-8,9-dihydroxy-7-methyl-3,4-dihydroanthracen-1(2H)-one; |
| Molecular form: | C52H76O24 |
| Appearance: | Yellow Solid |
| Mol. Weight: | 1085.16 |
| Storage: | 2-8°C Refrigerator, Under inert atmosphere |
| Shipping Conditions: | Ambient |
| Applications: | Mithramycin A is an anticancer antibiotic that selectively binds to G-C-rich DNA in the presence of Mg2+ or Zn2+, inhibiting RNA and DNA polymerase action. Mithramycin A inhibits c-myc expression and induces myeloid differentiation of HL-60 promyelocytic leukemia cells. |
Mithramycin A - API Standards
Mithramycin A
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