| Catalogue number: | PA 02 0751095 |
| Chemical name: | PC Biotin-PEG3-azide |
CAS Number: |
1937270-46-6 |
| Category: | intermediates,pharmaceutical standards,Fine Chemicals,biotin derivatives,Antibody Drug Conjugate |
| Synonyms: | 1-(4-((4,18-Dioxo-22-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-8,11,14-trioxa-5,17-diazadocosyl)oxy)-5-methoxy-2-nitrophenyl)ethyl (3-azidopropyl)carbamate; Carbamic acid, N-(3-azidopropyl)-, 1-[4-[[22-[(3aR,4R,6aS)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-4,18-dioxo-8,11,14-trioxa-5,17-diazadocos-1-yl]oxy]-5-methoxy-2-nitrophenyl]ethyl ester, rel-; rel-1-[4-[[22-[(3aR,4R,6aS)-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-4,18-dioxo-8,11,14-trioxa-5,17-diazadocos-1-yl]oxy]-5-methoxy-2-nitrophenyl]ethyl N-(3-azidopropyl)carbamate; |
| Molecular form: | C35H55N9O12S |
| Appearance: | Oil |
| Mol. Weight: | 825.94 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | PC Biotin-PEG3-azide is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. PC Biotin-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups |
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