| Catalogue number: | PA 27 0035709 |
| Chemical name: | 3-Aminophenyl Hemiasterlin |
CAS Number: |
1977557-86-0 |
| Category: | miscellaneous compounds,Antibody Drug Conjugate |
| Synonyms: | (S,E)-4-((S)-2-((S)-3-(3-aminophenyl)-3-methyl-2-(methylamino)butanamido)-N,3,3-trimethylbutanamido)-2,5-dimethylhex-2-enoic acid; L-Valinamide, 3-amino-N,β,β-trimethyl-L-phenylalanyl-N-[(1S,2E)-3-carboxy-1-(1-methylethyl)-2-buten-1-yl]-N,3-dimethyl-; 3-Amino-N,β,β-trimethyl-L-phenylalanyl-N-[(1S,2E)-3-carboxy-1-(1-methylethyl)-2-buten-1-yl]-N,3-dimethyl-L-valinamide; |
| Molecular form: | C27H44N4O4 |
| Appearance: | NA |
| Mol. Weight: | 488.67 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | SC209 (3-Aminophenyl Hemiasterlin) is a 3-aminophenyl hemiasterlin derivative that serves as a cytotoxin for ADCs, targeting tubulin. SC209 has reduced potential for drug efflux via P-glycoprotein 1 drug pump compared with other tubulin-targeting payloads. SC209 exhibits antitumor activity and can be used in the synthesis of ADC molecules |
3-Aminophenyl Hemiasterlin
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