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Catalogue number: PA 27 0035709
Chemical name: 3-Aminophenyl Hemiasterlin

CAS Number:

1977557-86-0

Category: miscellaneous compounds,Antibody Drug Conjugate
Synonyms:

(S,E)-4-((S)-2-((S)-3-(3-aminophenyl)-3-methyl-2-(methylamino)butanamido)-N,3,3-trimethylbutanamido)-2,5-dimethylhex-2-enoic acid; L-Valinamide, 3-amino-N,β,β-trimethyl-L-phenylalanyl-N-[(1S,2E)-3-carboxy-1-(1-methylethyl)-2-buten-1-yl]-N,3-dimethyl-; 3-Amino-N,β,β-trimethyl-L-phenylalanyl-N-[(1S,2E)-3-carboxy-1-(1-methylethyl)-2-buten-1-yl]-N,3-dimethyl-L-valinamide;

Molecular form: C27H44N4O4
Appearance: NA
Mol. Weight: 488.67
Storage: 2-8°C Refrigerator
Shipping Conditions: Ambient
Applications: SC209 (3-Aminophenyl Hemiasterlin) is a 3-aminophenyl hemiasterlin derivative that serves as a cytotoxin for ADCs, targeting tubulin. SC209 has reduced potential for drug efflux via P-glycoprotein 1 drug pump compared with other tubulin-targeting payloads. SC209 exhibits antitumor activity and can be used in the synthesis of ADC molecules

3-Aminophenyl Hemiasterlin

1977557-86-0
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