Catalogue number: | PA 27 0032391 |
Chemical name: | SC239 |
CAS Number: |
1977557-97-3 |
Category: | miscellaneous compounds,Antibody Drug Conjugate |
Synonyms: | L-Valinamide, 3-[[[[4-[[N-[4-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-1,4-dioxobutyl]-L-valyl-N5-(aminocarbonyl)-L-ornithyl]amino]phenyl]methoxy]carbonyl]amino]-N,β,β-trimethyl-L-phenylalanyl-N-[(1S,2E)-3-carboxy-1-(1-methylethyl)-2-buten-1-yl]-N,3-dimethyl-; 3-[[[[4-[[N-[4-(11,12-Didehydrodibenz[b,f]azocin-5(6H)-yl)-1,4-dioxobutyl]-L-valyl-N5-(aminocarbonyl)-L-ornithyl]amino]phenyl]methoxy]carbonyl]amino]-N,β,β-trimethyl-L-phenylalanyl-N-[(1S,2E)-3-carboxy-1-(1-methylethyl)-2-buten-1-yl]-N,3-dimethyl-L-valinamide; |
Molecular form: | C65H84N10O11 |
Appearance: | Solid |
Mol. Weight: | 1181.45 |
Storage: | 2-8°C Refrigerator |
Shipping Conditions: | Ambient |
Applications: | SC239 is a cleavable 2-aminophenyl hemiasterlin agent-linker. SC239 can be as the agent-linker for ADC[1]. SC239 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups |
SC239
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