Catalogue number: | PA PEP 002881 |
Chemical name: | α-Amanitin, 4-[6-[[4-[[N-[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]-L-valyl-L-alanyl]amino]phenyl]methoxy]-2-mercapto-L-tryptophan] |
CAS Number: |
2004724-36-9 |
Category: | peptides,Antibody Drug Conjugate |
Synonyms: | 4-[6-[[4-[[N-[3-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]-L-valyl-L-alanyl]amino]phenyl]methoxy]-2-mercapto-L-tryptophan]-α-amanitin; HDP 30.1699; |
Molecular form: | C61H80N14O19S |
Appearance: | Solid |
Mol. Weight: | 1345.45 |
Storage: | 2-8°C Refrigerator |
Shipping Conditions: | Ambient |
Applications: | HDP 30.1699, the derivative of α-Amanitin, shows considerable cross-links. The cysteine residues of the anti-HER2 THIOMAB antibody are used for conjugation of the cysteine reactive linker–Amanitin compound, HDP 30.1699, with a cleavable linker by maleimide chemistry |
α-Amanitin, 4-[6-[[4-[[N-[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]-L-valyl-L-alanyl]amino]phenyl]methoxy]-2-mercapto-L-tryptophan]
Enquire for α-Amanitin, 4-[6-[[4-[[N-[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]-L-valyl-L-alanyl]amino]phenyl]methoxy]-2-mercapto-L-tryptophan]
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