| Catalogue number: | PA 02 0751101 |
| Chemical name: | PC-Biotin-PEG4-PEG3-azide |
CAS Number: |
2055646-21-2 |
| Category: | intermediates,pharmaceutical standards,Fine Chemicals,biotin derivatives,Antibody Drug Conjugate |
| Synonyms: | 1-(5-(3,19-Dioxo-23-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-6,9,12,15-tetraoxa-2,18-diazatricosyl)-2-nitrophenyl)ethyl (2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethyl)carbamate; 5,8,11-Trioxa-2-azatridecanoic acid, 13-azido-, 1-[5-[23-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-3,19-dioxo-6,9,12,15-tetraoxa-2,18-diazatricos-1-yl]-2-nitrophenyl]ethyl Ester; 1-[5-[23-[(3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-3,19-dioxo-6,9,12,15-tetraoxa-2,18-diazatricos-1-yl]-2-nitrophenyl]ethyl 13-azido-5,8,11-trioxa-2-azatridecanoate; |
| Molecular form: | C39H63N9O14S |
| Appearance: | NA |
| Mol. Weight: | 914.04 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | PC-Biotin-PEG4-PEG3-azide is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. PC-Biotin-PEG4-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups |
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