| Catalogue number: | PA 02 0751104 |
| Chemical name: | Tetrazine-SS-Biotin |
CAS Number: |
2123482-78-8 |
| Category: | intermediates,pharmaceutical standards,Fine Chemicals,biotin derivatives,Antibody Drug Conjugate |
| Synonyms: | N-(2-((3-((4-(1,2,4,5-Tetrazin-3-yl)benzyl)amino)-3-oxopropyl)disulfaneyl)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide; 1H-Thieno[3,4-d]imidazole-4-pentanamide, hexahydro-2-oxo-N-[2-[[3-oxo-3-[[[4-(1,2,4,5-tetrazin-3-yl)phenyl]methyl]amino]propyl]dithio]ethyl]-, (3aS,4S,6aR)-; (3aS,4S,6aR)-Hexahydro-2-oxo-N-[2-[[3-oxo-3-[[[4-(1,2,4,5-tetrazin-3-yl)phenyl]methyl]amino]propyl]dithio]ethyl]-1H-thieno[3,4-d]imidazole-4-pentanamide; |
| Molecular form: | C24H32N8O3S3 |
| Appearance: | Solid |
| Mol. Weight: | 576.75 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | Tetrazine-SS-Biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Tetrazine-SS-Biotin is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups. |
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