| Catalogue number: | PA PEP 002995 |
| Chemical name: | DBCO-PEG4-VC-PAB-MMAE |
CAS Number: |
2129164-91-4 |
| Category: | peptides,Antibody Drug Conjugate |
| Synonyms: | NA |
| Molecular form: | C88H128N12O19 |
| Appearance: | Solid |
| Mol. Weight: | 1658.06 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | DBCO-PEG4-VC-PAB-MMAE consists a ADC linker (DBCO-PEG4-VC-PAB) and a tubulin polymerization inhibitor MMAE (HY-15162). DBCO-PEG4-VC-PAB-MMAE can be used in the synthesis of antibody-agent conjugates (ADCs). MMAE is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. DBCO-PEG4-VC-PAB-MMAE is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups |
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