Catalogue number: | PA 27 0032637 |
Chemical name: | BCN-exo-PEG7-maleimide |
CAS Number: |
2143965-47-1 |
Category: | miscellaneous compounds,Antibody Drug Conjugate |
Synonyms: | rel-((1R,8S,9r)-Bicyclo[6.1.0]non-4-yn-9-yl)methyl (27-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-25-oxo-3,6,9,12,15,18,21-heptaoxa-24-azaheptacosyl)carbamate; 5,8,11,14,17,20,23-Heptaoxa-2,26-diazanonacosanoic acid, 29-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-27-oxo-, (1α,8α,9α)-bicyclo[6.1.0]non-4-yn-9-ylmethyl Ester; (1α,8α,9α)-Bicyclo[6.1.0]non-4-yn-9-ylmethyl 29-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-27-oxo-5,8,11,14,17,20,23-heptaoxa-2,26-diazanonacosanoate; |
Molecular form: | C34H53N3O12 |
Appearance: | NA |
Mol. Weight: | 695.81 |
Storage: | 2-8°C Refrigerator |
Shipping Conditions: | Ambient |
Applications: | BCN-exo-PEG7-maleimide is an ADC Linker containing 7 PEG units. BCN-exo-PEG7-maleimide contains the lyophilic bidentate macrocyclic ligand BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies. |
BCN-exo-PEG7-maleimide
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