Catalogue number: | PA 27 0032669 |
Chemical name: | Azido-PEG5-CH2CO2H |
CAS Number: |
217180-81-9 |
Category: | miscellaneous compounds,Antibody Drug Conjugate |
Synonyms: | 17-Azido-3,6,9,12,15-pentaoxaheptadecanoic Acid; Acetic acid, 2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]-; 2-[2-[2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]acetic Acid; 3,6,9,12,15-Pentaoxaheptadecanoic acid, 17-azido-; |
Molecular form: | C12H23N3O7 |
Appearance: | Liquid |
Mol. Weight: | 321.33 |
Storage: | 2-8°C Refrigerator |
Shipping Conditions: | Ambient |
Applications: | Azido-PEG5-CH2CO2H is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG5-CH2CO2H is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG5-CH2CO2H is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups |
Azido-PEG5-CH2CO2H
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