Propargyl-PEG8-NHS ester

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Catalogue number:	PA 27 0030197
Chemical name:	Propargyl-PEG8-NHS ester
CAS Number:	2182601-74-5
Category:	miscellaneous compounds,Antibody Drug Conjugate,Linkers
Synonyms:	2,5-dioxopyrrolidin-1-yl 4,7,10,13,16,19,22,25-octaoxaoctacos-27-ynoate; 4,7,10,13,16,19,22,25-Octaoxaoctacos-27-ynoic acid, 2,5-dioxo-1-pyrrolidinyl ester; 2,5-Dioxo-1-pyrrolidinyl 4,7,10,13,16,19,22,25-octaoxaoctacos-27-ynoate;
Molecular form:	C₂₄H₃₉NO₁₂
Appearance:	Liquid
Mol. Weight:	533.57
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	Propargyl-PEG8-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG8-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-PEG8-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups