| Catalogue number: | PA 27 0032670 |
| Chemical name: | Amidate-VC-PAB-MMAF |
CAS Number: |
2202782-90-7 |
| Category: | miscellaneous compounds,Antibody Drug Conjugate |
| Synonyms: | ((2R,3R)-3-((2S)-1-((3R,4S,5S)-4-((2S)-2-((2S)-2-((((4-((2S)-2-((2S)-2-(4-((Ethoxy(ethynyl)phosphoryl)amino)benzamido)-3-methylbutanamido)-5-ureidopentanamido)benzyl)oxy)carbonyl)(methyl)amino)-3-methylbutanamido)-N,3-dimethylbutanamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanoyl)-L-phenylalanine; |
| Molecular form: | C69H102N11O16P |
| Appearance: | NA |
| Mol. Weight: | 1372.61 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | Amidate-VC-PAB-MMAF consists a cleavable ADC linker (Amidate-VC-PAB) and a potent tubulin polymerization inhibitor (MMAF). Amidate-VC-PAB-MMAF can be used in the synthesis of antibody-drug conjugates (ADCs). Amidate-VC-PAB-MMAF reduces off-target cytotoxicity of ADCs[1] |
Amidate-VC-PAB-MMAF
Amidate-VC-PAB-MMAF
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