Amidate-VC-PAB-MMAF

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Catalogue number:	PA 27 0032670
Chemical name:	Amidate-VC-PAB-MMAF
CAS Number:	2202782-90-7
Category:	miscellaneous compounds,Antibody Drug Conjugate
Synonyms:	((2R,3R)-3-((2S)-1-((3R,4S,5S)-4-((2S)-2-((2S)-2-((((4-((2S)-2-((2S)-2-(4-((Ethoxy(ethynyl)phosphoryl)amino)benzamido)-3-methylbutanamido)-5-ureidopentanamido)benzyl)oxy)carbonyl)(methyl)amino)-3-methylbutanamido)-N,3-dimethylbutanamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanoyl)-L-phenylalanine;
Molecular form:	C₆₉H₁₀₂N₁₁O₁₆P
Appearance:	NA
Mol. Weight:	1372.61
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	Amidate-VC-PAB-MMAF consists a cleavable ADC linker (Amidate-VC-PAB) and a potent tubulin polymerization inhibitor (MMAF). Amidate-VC-PAB-MMAF can be used in the synthesis of antibody-drug conjugates (ADCs). Amidate-VC-PAB-MMAF reduces off-target cytotoxicity of ADCs[1]