Catalogue number: | PA PEP 001470 |
Chemical name: | SC-VC-PAB-MMAE |
CAS Number: |
2259318-46-0 |
Category: | peptides,Antibody Drug Conjugate |
Synonyms: | 2,5-dioxopyrrolidin-1-yl 6-(((S)-1-(((S)-1-((4-((5S,8S,11S,12R)-11-((S)-sec-butyl)-12-(2-((S)-2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidin-1-yl)-2-oxoethyl)-5,8-diisopropyl-4,10-dimethyl-3,6,9-trioxo-2,13-dioxa-4,7,10-triazatetradecyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)amino)-6-oxohexanoate; |
Molecular form: | C68H105N11O17 |
Appearance: | Solid |
Mol. Weight: | 1348.65 |
Storage: | 2-8°C Refrigerator |
Shipping Conditions: | Ambient |
Applications: | SC-VC-PAB-MMAE is a agent-linker conjugate for ADC with potent antitumor activity by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked via the cleavable linker SC-VC-PAB[ |
SC-VC-PAB-MMAE
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