Taltobulin trifluoroacetate

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Catalogue number: PA PEP 003155
Chemical name: Taltobulin trifluoroacetate

CAS Number:

228266-41-9

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Category: peptides,Antibody Drug Conjugate
Synonyms:

(S,E)-2,5-Dimethyl-4-((S)-N,3,3-trimethyl-2-((S)-3-methyl-2-(methylamino)-3-phenylbutanamido)butanamido)hex-2-enoic acid--2,2,2-trifluoroacetic acid (1/1); L-Valinamide, N,β,β-trimethyl-L-phenylalanyl-N-[(1S,2E)-3-carboxy-1-(1-methylethyl)-2-butenyl]-N,3-dimethyl-, mono(trifluoroacetate);

Molecular form: C29H44F3N3O6
Appearance: Solid
Mol. Weight: 587.68
Storage: 2-8°C Refrigerator
Shipping Conditions: Ambient
Applications: Taltobulin trifluoroacetate (HTI-286 trifluoroacetate), a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo. Taltobulin trifluoroacetate inhibits the polymerization of purified tubulin, disrupts microtubule organization in cells, and induces mitotic arrest, as well as apoptosis

Taltobulin trifluoroacetate

228266-41-9
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