| Catalogue number: | PA 27 0032940 |
| Chemical name: | TCO-GK-PEG4-NHS ester |
CAS Number: |
2307311-19-7 |
| Category: | miscellaneous compounds,Antibody Drug Conjugate |
| Synonyms: | (22S)-22-(2-(((((Z)-Cyclooct-4-en-1-yl)oxy)carbonyl)amino)acetamido)-1-((2,5-dioxopyrrolidin-1-yl)oxy)-1,16-dioxo-4,7,10,13-tetraoxa-17-azatricosan-23-oic Acid; L-Lysine, N-[(4-cycloocten-1-yloxy)carbonyl]glycyl-N6-[16-[(2,5-dioxo-1-pyrrolidinyl)oxyl]-1,16-dioxo-4,7,10,13-tetraoxahexadec-1-yl]-; N-[(4-Cycloocten-1-yloxy)carbonyl]glycyl-N6-[16-[(2,5-dioxo-1-pyrrolidinyl)oxyl]-1,16-dioxo-4,7,10,13-tetraoxahexadec-1-yl]-L-lysine; |
| Molecular form: | C33H52N4O14 |
| Appearance: | NA |
| Mol. Weight: | 728.79 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | TCO-GK-PEG4-NHS ester is an ADC Linker, and can be used for synthesis of [18F]AlF-NOTA-Tz-TCO-GK-2Rs15d. [18F]AlF-NOTA-Tz-TCO-GK-2Rs15d binds with high affinity and immunoreactivity to HER2[1]. TCO-GK-PEG4-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups. |
TCO-GK-PEG4-NHS ester
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