| Catalogue number: | PA PHY 004575 |
| Chemical name: | Paeoniflorin |
CAS Number: |
23180-57-6 |
| Category: | NA |
| Synonyms: | ((1aR,1a1S,2S,3aR,5R,5aR)-5-Hydroxy-2-methyl-1a-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-1H-3,4-dioxa-2,5-methanocyclobuta[cd]pentalen-1a1(3aH)-yl)methyl benzoate; Peoniflorin; [1aR-(1aα,2β,3aα,5α,5aα,5bα)]-5b-[(Benzoyloxy)methyl]tetrahydro-5-hydroxy-2-methyl-2,5-methano-1H-3,4-dioxacyclobuta[cd]pentalen-1a(2H)-yl β-D-Glucopyranoside; 2,5-Methano-1H-3,4-dioxacyclobuta[cd]pentalene β-D-Glucopyranoside Deriv.; ((2S,2aR,2a1S,3aR,4R,5aR)-4-Hydroxy-2-methyl-2a-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexahydro-2H-1,5-dioxa-2,4-methanocyclobuta[cd]pentalen-2a1-yl)methyl Benzoate; |
| Molecular form: | C23H28O11 |
| Appearance: | White to off-White Solid |
| Mol. Weight: | 480.5 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | Paeoniflorin is an active compound of the Paeonia root. Paeoniflorin inhibits A?25-35-induced mitochondrial dysfunction, which includes decreased mitochondrial membrane potential, increased Bax/Bcl-2 ratio, cytochrome c release and activity of caspase-3 and caspase-9. Paeoniflorin could attenuate or restore the viability loss, apoptotic increase, and ROS production induced by A?25-35 in SH-SY5Y cells. |
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