Catalogue number: | PA 27 0032912 |
Chemical name: | PSMA-azide |
CAS Number: |
2374814-84-1 |
Category: | miscellaneous compounds,Antibody Drug Conjugate |
Synonyms: | (3S,7S,25S,28S)-33-Azido-25-benzyl-12-(3-chlorobenzyl)-28-(4-hydroxybenzyl)-5,13,20,23,26,29-hexaoxo-4,6,12,19,24,27,30-heptaazatritriacontane-1,3,7-tricarboxylic Acid; |
Molecular form: | C50H65ClN10O13 |
Appearance: | Solid |
Mol. Weight: | 1049.58 |
Storage: | 2-8°C Refrigerator |
Shipping Conditions: | Ambient |
Applications: | PSMA-azide is a prostate-specific membrane antigen (PSMA) ligand. PSMA-azide inhibits PSMA-dependent NAAG (N-acetylaspartylglutamic acid) hydrolysis, with an IC50 of 9 nM and a Ki of 1 nM. PSMA-azide contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups |
PSMA-azide
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