| Catalogue number: | PA 27 0033054 |
| Chemical name: | Fmoc-L-Lys(Pentynoyl-DIM)-OH |
CAS Number: |
2408993-33-7 |
| Category: | miscellaneous compounds,Antibody Drug Conjugate |
| Synonyms: | N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N6-(1-(4,4-dimethyl-2,6-dioxocyclohexylidene)pent-4-yn-1-yl)-L-lysine; L-Lysine, N6-[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-4-pentyn-1-yl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-; N6-[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)-4-pentyn-1-yl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-lysine; |
| Molecular form: | C34H38N2O6 |
| Appearance: | NA |
| Mol. Weight: | 570.69 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | Fmoc-L-Lys(Pentynoyl-DIM)-OH is a click chemistry reagent containing an azide. Fmoc-L-Lys(Pentynoyl-DIM)-OH can be used as a SPPS building block for the “helping hand” strategy for purification of highly insoluble peptides. Solubilizing residues are attached to the Lys side-chains using Click-chemistry. The solubilizing tag can be removed with 1M hydrazine or hydroxylamine solution[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups |
Fmoc-L-Lys(Pentynoyl-DIM)-OH
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