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Catalogue number: PA 01 06000
Chemical name: Acadesine

CAS Number:

2627-69-2

Category: bases and related reagents,nucleotides,carbohydrates
Synonyms:

5-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-imidazole-4-carboxamide; Imidazole-4-carboxamide, 5-amino-1-β-D-ribofuranosyl; 1-β-D-Ribofuranosyl-5-amino-4-imidazolecarboxamide; 5-Amino-1-ribosyl-4-imidazolecarboxamide; 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside; AICAR; Acadesine; 5-Amino-1-β-D-ribofuranosyl-1H-imidazole-4-carboxamide; 5-Amino-4-imidazole carboxamide Riboside; Arasine; GP 1-110;

Molecular form: C9H14N4O5
Appearance: Off-White to Pale Beige Solid
Mol. Weight: 258.23
Storage: 2-8°C Refrigerator
Shipping Conditions: Ambient
Applications: Acadesine (AICA-riboside) is a purine nucleoside analog with anti-ischemic properties that is currently being studied (Phase 3) for the prevention of adverse cardiovascular outcomes in patients undergoing coronary artery bypass graft (CABG) surgery. It is being developed jointly by PeriCor and Schering-Plough. Acadesine has been granted Orphan Drug Designation for B-CLL in the EU.

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