XMT-1519 conjugate-1

2720500-19-4

3-((5-Carbamoyl-1-((E)-4-(6-carbamoyl-2-(4-ethyl-2-methyloxazole-5-carboxamido)-3H-imidazo[4,5-b]pyridin-3-yl)but-2-en-1-yl)-2-(4-ethyl-2-methyloxazole-5-carboxamido)-1H-benzo[d]imidazol-7-yl)oxy)propyl ((S)-1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-2,7-dioxo-4-((2-oxo-2-((2-oxo-2-((2-oxo-2-(((32S,38S,39R,40R,41R)-38,39,40,41,42-pentahydroxy-2,30,35-trioxo-32-(((2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl)carbamoyl)-6,9,12,15,18,21,24,27-octaoxa-3,31,36-triazadotetracontyl)amino)ethyl)amino)ethyl)amino)ethyl)carbamoyl)-11,14-dioxa-3,8-diazaheptadecan-17-oyl)-L-alaninate; D-Glucitol, 1,1′-[[N5-[(11S)-16-[[5-(aminocarbonyl)-1-[(2E)-4-[6-(aminocarbonyl)-2-[[(4-ethyl-2-methyl-5-oxazolyl)carbonyl]amino]-3H-imidazo[4,5-b]pyridin-3-yl]-2-buten-1-yl]-2-[[(4-ethyl-2-methyl-5-oxazolyl)carbonyl]amino]-1H-benzimidazol-7-yl]oxy]-11-methyl-9,12-dioxo-3,6,13-trioxa-10-azahexadec-1-yl]-N2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)acetyl]-L-glutaminylglycylglycylglycylglycyl-27-amino-4,7,10,13,16,19,22,25-octaoxaheptacosanoyl-L-glutamoyl]diimino]bis[1-deoxy-; 1,1′-[[N5-[(11S)-16-[[5-(Aminocarbonyl)-1-[(2E)-4-[6-(aminocarbonyl)-2-[[(4-ethyl-2-methyl-5-oxazolyl)carbonyl]amino]-3H-imidazo[4,5-b]pyridin-3-yl]-2-buten-1-yl]-2-[[(4-ethyl-2-methyl-5-oxazolyl)carbonyl]amino]-1H-benzimidazol-7-yl]oxy]-11-methyl-9,12-dioxo-3,6,13-trioxa-10-azahexadec-1-yl]-N2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)acetyl]-L-glutaminylglycylglycylglycylglycyl-27-amino-4,7,10,13,16,19,22,25-octaoxaheptacosanoyl-L-glutamoyl]diimino]bis[1-deoxy-D-glucitol];