Catalogue number: | PA PHY 003951 |
Chemical name: | Cyclopamine |
CAS Number: |
4449-51-8 |
Category: | NA |
Synonyms: | (3S,3'R,3a'S,6aS,6bS,6'S,7a'R,9R,11aS,11bR)-3',6',10,11b-Tetramethyl-1,2,3,3a',4,4',5',6,6a,6b,6',7,7',7a',8,11,11a,11b-octadecahydro-3'H-spiro[benzo[a]fluorene-9,2'-furo[3,2-b]pyridin]-3-ol; (2’R,3S,3’R,3’aS,6’S,6aS,6bS,7’aR,11aS,11bR)-1,2,3,3’a,4,4’,5’,6,6’,6a,6b,7,7’,7’a,8,11,11a,11b-Octadecahydro-3’,6’,10,11b-tetramethylspiro[9H-benzo[a]fluorene-9,2’(3’H)-furo[3,2-b]pyridin]-3-ol; 11-Deoxojervine; (3β,23β)-17,23-Epoxyveratraman-3-ol; 11-Deoxyjervine; |
Molecular form: | C27H41NO2 |
Appearance: | White to Off-White Solid |
Mol. Weight: | 411.6 |
Storage: | 2-8°C Refrigerator |
Shipping Conditions: | Ambient |
Applications: | Cyclopamine antibacterial properties. Cyclopamine demonstrates teratogenic properties and has been shown to reverse effects of oncogenic mutations in Smoothened and Patched. Potent Hedgehog inhibitor Solubility: 1mg of Cyclopamine dissolves in 0.2ml DMSO with heating to approximately 70 degrees (ca. 12 mmol sol.)_x000B_Solubility: 4mg of Cyclopamine dissolves in 1ml 95% Ethanol |
Cyclopamine
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