Catalogue number: | PA PHY 004844 |
Chemical name: | Withaferin A |
CAS Number: |
5119-48-2 |
Category: | NA |
Synonyms: | (4S,4aR,5aR,6aS,6bS,9R,9aS,11aS,11bR)-4-Hydroxy-9-((S)-1-((R)-5-(hydroxymethyl)-4-methyl-6-oxo-3,6-dihydro-2H-pyran-2-yl)ethyl)-9a,11b-dimethyl-5a,6,6a,6b,7,8,9,9a,10,11,11a,11b-dodecahydrocyclopenta[1,2]phenanthro[8a,9-b]oxiren-1(4H)-one; 5β-Ergosta-2,24-dien-26-oic acid, 5,6β-epoxy-4β,22,27-trihydroxy-1-oxo-, δ-lactone, (20S,22R)-;Withaferine; Withaferine A; |
Molecular form: | C28H38O6 |
Appearance: | White to Off-White Solid |
Mol. Weight: | 470.6 |
Storage: | 2-8°C Refrigerator |
Shipping Conditions: | Ambient |
Applications: | Withaferin A is a promising anticancer constituent of Ayurvedic medicinal plant Withania somnifera. Withaferin A showed potent cytotoxicity against human head and neck squamous cell carcinoma (JMAR and MDA-1986). Withaferin A has recently been found to be a leptin sensitizer that can reduce the weight in obese mice fed in a high-fat diet (see C249500). |
Withaferin A
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