| Catalogue number: | PA 21 0031006 |
| Chemical name: | 5,6-Dihydrouridine |
CAS Number: |
5627-05-4 |
| Category: | impurities,metabolites,pharmaceutical standards,intermediates,Fine Chemicals |
| Synonyms: | 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)dihydropyrimidine-2,4(1H,3H)-dione; Uridine, 5,6-dihydro; Hydrouracil, 1-β-D-ribofuranosyl; 2,4(1H,3H)-Pyrimidinedione, dihydro-1-β-D-ribofuranosyl; Dihydrouridine; |
| Molecular form: | C9H14N2O6 |
| Appearance: | White to Off-White Solid |
| Mol. Weight: | 246.22 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | 5,6-Dihydrouridine is an intermediate used in the synthesis of 3,4,5,6-Tetrahydrouridine, which is a derivative of Uridine. Tetrahydrouridine (THU) is a potent inhibitor of cytidine. It inhibits cell proliferation through cell cycle regulation regardless of cytidine deaminase expression levels deaminase (CDA), and thus can be used as a potential and promising treatment for tumors with highly expressed CDA. |
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