Catalogue number: | PA 19 1780000 |
Chemical name: | Sapropterin |
CAS Number: |
62989-33-7 |
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Category: | impurities,metabolites,pharmaceutical standards,intermediates,Fine Chemicals |
Synonyms: | (R)-2-amino-6-((1R,2S)-1,2-dihydroxypropyl)-5,6,7,8-tetrahydropteridin-4(1H)-one; (6R)-2-Amino-6-[(1R,2S)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydro-4(1H)-pteridinone; 4(1H)-Pteridinone, 2-amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-, [6R-[6R*(1R*,2S*)]]; (6R)-5,6,7,8-Tetrahydro-L-biopterin; (6R)-5,6,7,8-Tetrahydrobiopterin; (6R)-L-erythro-5,6,7,8-Tetrahydrobiopterin; (6R)-L-erythro-Tetrahydrobiopterin; (6R)-Tetrahydrobiopterin; (6R)-Tetrahydrobiopterin; 6R-Tetrahydro-L-biopterin; 6β-5,6,7,8-Tetrahydro-L-biopterin; Tetrahydrobiopterin; |
Molecular form: | C9H15N5O3 |
Appearance: | NA |
Mol. Weight: | 241.25 |
Storage: | 2-8°C Refrigerator |
Shipping Conditions: | Ambient |
Applications: | Sapropterin is a cofactor used as an adjunct to phenylalanine restriction in the treatment of phenylketonuria (PKU). Sapropterin (tetrahydrobiopterin or BH4) is a cofactor in the synthesis of nitric oxide. It is also essential in the conversion of phenylalanine to tyrosine by the enzyme phenylalanine-4-hydroxylase; the conversion of tyrosine to L-dopa by the enzyme tyrosine hydroxylase; and conversion of tryptophan to 5-hydroxytryptophan via tryptophan hydroxylase. |
Sapropterin - API
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