| Catalogue number: | PAI 20 002511 |
| Chemical name: | 1-(3-Chlorophenyl)piperazine |
CAS Number: |
6640-24-0 |
| Similar Products: | |
| Category: | intermediates |
| Synonyms: | Trazodone Hydrochloride Impurity L (EP/BP); 1-(m-Chlorophenyl)piperazine; 4-(3-Chlorophenyl)piperazine; N-(3-Chlorophenyl)piperazine; N-(m-Chlorophenyl)piperazine; meta-Chlorophenylpiperazine; mCPP; |
| Molecular form: | C10H13ClN2 |
| Appearance: | Colourless Oil |
| Mol. Weight: | 196.68 |
| Storage: | 2-8°C Refrigerator, Under inert atmosphere |
| Shipping Conditions: | Ambient |
| Applications: | It is noteworthy that 1-(3-Chlorphenyl)piperazine (m-CPP), resulting from N-dealkylation of Trazodone, is a major circulating metabolite in humans common to several antidepressants including Trazodone, Nefazodone, and Etoperidone (1,2,3). The metabolite m-CPP is of significant interest because it has 5-HT2C agonistic and 5-HT2A antagonistic properties. It has also been suggested that m-CPP may contribute to the antidepressant efficacy of Trazodone. |
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