| Catalogue number: | PA 27 0016946 |
| Chemical name: | (+/-)-Blebbistatin |
CAS Number: |
674289-55-5 |
| Category: | miscellaneous compounds |
| Synonyms: | 3a-Hydroxy-6-methyl-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one; |
| Molecular form: | C18H16N2O2 |
| Appearance: | Yellow Solid |
| Mol. Weight: | 292.34 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | Blebbistatin blocked myosin II-dependent cell processes. It blocks cell blebbing rapidly and reversibly. Also rapidly disrupted directed cell migration and cytokinesis in vertebrate cell. It blocks both blebbing and cytokinesis at 50-100µM.(±)-1-Phenyl-1,2,3,4-tetrahydro-4-hydroxypyrrolo[2,3-b]-7-methylquinolin-4-one_x000B__x000B_Selective inhibitor of nonmuscle myosin II; inhibits contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly. Rapidly and reversibly blocks cell blebbing, and disrupts directed cell migration and cytokinesis in vertebrate cells. |
(+/-)-Blebbistatin
(+/-)-Blebbistatin
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