| Catalogue number: | PA 13 3400000 |
| Chemical name: | Methotrexate Monohydrate |
CAS Number: |
6745-93-3 |
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| Category: | impurities,metabolites,pharmaceutical standards,Intermediates,Fine Chemicals,Antibody Drug Conjugate |
| Synonyms: | (4-(((2,4-Diaminopteridin-6-yl)methyl)(methyl)amino)benzoyl)-L-glutamic acid hydrate; L-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, monohydrate; Glutamic acid, N-[p-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, monohydrate, L-; |
| Molecular form: | C20H24N8O6 |
| Appearance: | NA |
| Mol. Weight: | 472.46 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | Methotrexate (Amethopterin) monohydrate, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis. Methotrexate monohydrate, also an immunosuppressant and antineoplastic agent, is used for the research of rheumatoid arthritis and a number of different cancers (such as acute lymphoblastic leukemia) |
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