| Catalogue number: | PA STI 032740 |
| Chemical name: | trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene-d8 |
CAS Number: |
861441-06-7 |
| Category: | miscellaneous compounds,stable isotopes |
| Synonyms: | (7R,8R)-rel-7,8-Dihydrobenzo[a]pyrene-1,2,3,4,5,6,11,12-d8-7,8-diol; Benzo[a]pyrene-1,2,3,4,5,6,11,12-d8-7,8-diol, 7,8-dihydro-, (7R,8R); |
| Molecular form: | C20H6D8O2 |
| Appearance: | NA |
| Mol. Weight: | 294.37 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | Labelled trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene is a metabolite of Benzopyrene. Benzo[a]pyrene, a prototypic PAH, is metabolized by cytochrome P 450 1A1/1B1. (-)-trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene undergoes further P 4501A1/1B1-mediated metabolism to a carcinogen, which forms DNA-adducts primarily with 2'-deoxyguanosine. A carcinogen. |
trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene-d8
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