| Catalogue number: | PA 43 0341014 |
| Chemical name: | Methyl ((2R,3R)-3-methoxy-2-methyl-3-((S)-pyrrolidin-2-yl)propanoyl)-L-phenylalaninate Hydrochloride |
CAS Number: |
864238-20-0 |
| Category: | pharmaceutical standards,amino acid derivatives,Antibody Drug Conjugate |
| Synonyms: | L-Phenylalanine, N-[(2R,3R)-3-methoxy-2-methyl-1-oxo-3-(2S)-2-pyrrolidinylpropyl]-, methyl ester, Monohydrochloride; |
| Molecular form: | C19H29ClN2O4 |
| Appearance: | NA |
| Mol. Weight: | 384.9 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | MMAF intermediate 2 is an intermediate for the synthesis of MMAF (HY-15579). MMAF (Monomethylauristatin F) is a potent inhibitor of tubulin polymerization and the cytotoxic (ADC Cytotoxin) component of classic antibody drug conjugates (ADCs), such as Vorsetuzumab mafodotin and SGN-CD19A |
Methyl ((2R,3R)-3-methoxy-2-methyl-3-((S)-pyrrolidin-2-yl)propanoyl)-L-phenylalaninate Hydrochloride
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