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Catalogue number: PA 18 1230000
Chemical name: Revefenacin

CAS Number:

864750-70-9

Category: impurities,metabolites,pharmaceutical standards,intermediates,Fine Chemicals
Synonyms:

Carbamic acid, N-[1,1'-biphenyl]-2-yl-, 1-[2-[[4-[[4-(aminocarbonyl)-1-piperidinyl]methyl]benzoyl]methylamino]ethyl]-4-piperidinyl ester; 1-[2-(1-{4-[(4-Carbamoylpiperidin-1-yl)methyl]phenyl}-N-methylformamido)ethyl]piperidin-4-yl N-{[1,1'-biphenyl]-2-yl}carbamate;

Molecular form: C35H43N5O4
Appearance: NA
Mol. Weight: 597.76
Storage: 2-8°C Refrigerator
Shipping Conditions: Ambient
Applications: Revefenacin is a novel biphenyl carbamate tertiary amine agent that belongs to the family of the long-acting muscarinic antagonists (LABA). The labile primary amide in the structure produces a "soft-drug" site that allows rapid systemic clearance and minimizing of the systemically mediated adverse reactions. The LABA group falls into a parent category known as long-acting inhaled bronchodilators and this type of agents are recommended as a maintenance therapy for chronic obstructive pulmonary disease (COPD).1 From the LABA group, revefenacin is the first once-daily nebulized LAMA treatment.2 It was developed by Theravance Biopharma and FDA approved on November 9, 2018.8

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