| Catalogue number: | PA 27 0035784 |
| Chemical name: | 2,5-Dioxopyrrolidin-1-yl 6-azidohexanoate |
CAS Number: |
866363-70-4 |
| Category: | miscellaneous compounds,Antibody Drug Conjugate |
| Synonyms: | Hexanoic acid, 6-azido-, 2,5-dioxo-1-pyrrolidinyl ester; 2,5-Pyrrolidinedione, 1-[(6-azido-1-oxohexyl)oxy]-; (2,5-Dioxopyrrolidin-1-yl) 6-azidohexanoate; 1-[(6-Azidohexanoyl)oxy]pyrrolidine-2,5-dione; 6-Azidohexanoic acid N-hydroxysuccinimide; |
| Molecular form: | C10H14N4O4 |
| Appearance: | NA |
| Mol. Weight: | 254.25 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | N3-C5-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N3-C5-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups |
2,5-Dioxopyrrolidin-1-yl 6-azidohexanoate
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