| Catalogue number: | PA STI 082570 |
| Chemical name: | TH-302-d8 |
CAS Number: |
918632-75-4 |
| Category: | stable isotopes,miscellaneous compounds |
| Synonyms: | N,N'-Bis(2-bromoethyl)phosphorodiamidic Acid-d8 (1-Methyl-2-nitro-1H-imidazol-5-yl)methyl Ester; |
| Molecular form: | C9H8D8Br2N5O4P |
| Appearance: | NA |
| Mol. Weight: | 457.09 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | TH-302-d8 is the isotope labelled analog of TH-302, a 2-nitroimidazole triggered hypoxia-activated prodrug (HAP) of bromo-isophosphoramide mustard. Studies have shown that TH-302 treatment exhibited hypoxia-selective cytotoxicity and DNA damage in human cancer cell. |
| BTM: | NA |
TH-302-d8
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