| Catalogue number: | PA 27 0035736 |
| Chemical name: | 2,5-Dioxopyrrolidin-1-yl 4-azidobutanoate |
CAS Number: |
943858-70-6 |
| Category: | miscellaneous compounds,Antibody Drug Conjugate |
| Synonyms: | Butanoic acid, 4-azido-, 2,5-dioxo-1-pyrrolidinyl ester; 2,5-Dioxo-1-pyrrolidinyl 4-azidobutanoate; (2,5-Dioxopyrrolidin-1-yl) 4-azidobutanoate; 4-Azidobutyrate N-hydroxysuccinimide ester; |
| Molecular form: | C8H10N4O4 |
| Appearance: | NA |
| Mol. Weight: | 226.19 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | N3-C3-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N3-C3-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. |
2,5-Dioxopyrrolidin-1-yl 4-azidobutanoate
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