| Catalogue number: | PA PHY 004318 |
| Chemical name: | ISOLIQUIRITIGENIN |
CAS Number: |
961-29-5 |
| Category: | NA |
| Synonyms: | (2E)-1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one; ISL; 2’,4,4’-Trihydroxychalcone; 2’,4,4’-Trihydroxychalcone; GU 17 |
| Molecular form: | C15H12O4 |
| Appearance: | Yellow Solid |
| Mol. Weight: | 256.25 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | Isoliquiritigenin (ISL) is a flavonoid found in licorice root and several other plants that displays antioxidant, anti-inflammatory, and antitumor activities as well as hepatoprotection against steatosis-induced oxidative stress. ISL induces quinone reductase-1, a phase II enzyme that deactivates radicals and electrophiles, with a concentration required to double activity (CD) value of 1.8 ?M in murine hepatoma cells. |
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