| Catalogue number: | PA STI 089345 |
| Chemical name: | CHIR-99021-d4 |
CAS Number: |
NA |
| Alternate CAS Number: | 252917-06-9 (Unlabelled) |
| Category: | stable isotopes |
| Synonyms: | 6-((2-((4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl-1,1,2,2-d4)amino)nicotinonitrile; |
| Molecular form: | C22H14D4Cl2N8 |
| Appearance: | NA |
| Mol. Weight: | 469.37 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | CHIR-99021-d4 is the deuterized or labeled form of CHIR-99021 Hydrochloride, which is a potent and highly selective inhibitor of glycogen synthase kinases 3 (GSK-3). CHIR-99021 activates glycogen synthesis in CHO-IR cells and in isolated type 1 diabetic rat skeletal muscle. CHIR-99021 has also been shown to induce the reprogramming of murine and human somatic cells into stem cells. |
CHIR-99021-d4
CHIR-99021-d4
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