Ixabepilone System Suitability Mixture

NA

(1S,3S,7S,10R,11S,12S,16R)-7,11-dihydroxy-8,8,10,12,16-pentamethyl-3-[(E)-1-(2-methylthiazol-4-yl)prop-1-en-2-yl]-17-oxa-4-azabicyclo[14.1.0]heptadecane-5,9-dione and (4S,7R,8S,9S,13R,14R,16S)-4,8,13,14-tetrahydroxy-5,5,7,9,13-pentamethyl-16-[(E)-1-(2-methylthiazol-4-yl)prop-1-en-2-yl]azacyclohexadecane-2,6-dione and (1R,2R,6S,7S,8R,11S,15S)-2,7,11-Trihydroxy-2,6,8,10,10-pentamethyl15-[(E)-1-(2-methylthiazol-4-yl)prop1-en-2-yl]-17-oxa-14-azabicyclo[11.3.1]heptadec-13-en-9-one and (1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-8,8,10,12-tetramethyl-3-[(E)-1-(2-methylthiazol-4-yl)prop-1-en-2-yl]-17-oxa-4-azabicyclo[14.1.0]heptadecane-5,9-dione and (1S,3S,7S,10R,11S,12S,16R)-7,11-dihydroxy-8,8,10,12,16-pentamethyl-3-[(Z)-1-(2-methylthiazol-4-yl)prop-1-en-2-yl]-17-oxa-4-azabicyclo[14.1.0]heptadecane-5,9-dione; This is a mixture of Ixabepilone and small amounts of Ixabepilone diol, Ixabepilone Oxazine analog,Desmethyl Ixabepilone, and (Z)-Ixabepilone (USP);